Team:Wisconsin/Modeling

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<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert *** -->
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<html><link rel="stylesheet" href="https://mywebspace.wisc.edu/jluo1/wisconsinstyle.css" type="text/css"></html>
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<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
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This is a template page. READ THESE INSTRUCTIONS.
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2008.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, and a lab notebook.  PLEASE keep all of your pages within your Team:Example namespace. 
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{|
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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|[[Image:Example_logo.png|200px|right|frame]]
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''Tell us more about your project.  Give us background.  Use this is the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|align="center"|[[Team:Wisconsin | Team Example 2]]
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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!align="center"|[[Team:Wisconsin|Home]]
!align="center"|[[Team:Wisconsin|Home]]
!align="center"|[[Team:Wisconsin/Team|The Team]]
!align="center"|[[Team:Wisconsin/Team|The Team]]
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!align="center"|[[Team:Wisconsin/Modeling|Modeling]]
!align="center"|[[Team:Wisconsin/Modeling|Modeling]]
!align="center"|[[Team:Wisconsin/Notebook|Notebook]]
!align="center"|[[Team:Wisconsin/Notebook|Notebook]]
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(''Or you can choose different headings.  But you must have a team page, a project page, and a notebook page.'')
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===Note===
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==Computer Modeling==
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Our modeling adventure started with a brief introduction to programming using GAMS software and an ''E. coli'' database developed by Dr. Jennie Reed at the University of Wisconsin College of Engineering.  Dr. Reed’s database works in conjunction with the GAMS software to measure metabolic fluxes in ''E. coli''. Using this as a base point we were able to computationally manipulate metabolites, genes, and the growth environment to determine the most optimal conditions for cell growth and hopefully sorbitol production.  Glycerol is currently produced at a rate of one pound for every ten pounds of biodiesel produced.  Consequently, our team felt it would be interesting if we could find a novel use for glycerol in our pursuit of sorbitol producing ''E. coli''. As such we decided to utilize glycerol as our growth media carbon source.  After many hours spent running simulations we identified several potential candidates which we are currently working with.
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If you choose to include a '''Modeling''' page, please write about your modeling adventures here. This is not necessary but it may be a nice list to include.
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Latest revision as of 00:27, 30 October 2008

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Computer Modeling


Our modeling adventure started with a brief introduction to programming using GAMS software and an E. coli database developed by Dr. Jennie Reed at the University of Wisconsin College of Engineering. Dr. Reed’s database works in conjunction with the GAMS software to measure metabolic fluxes in E. coli. Using this as a base point we were able to computationally manipulate metabolites, genes, and the growth environment to determine the most optimal conditions for cell growth and hopefully sorbitol production. Glycerol is currently produced at a rate of one pound for every ten pounds of biodiesel produced. Consequently, our team felt it would be interesting if we could find a novel use for glycerol in our pursuit of sorbitol producing E. coli. As such we decided to utilize glycerol as our growth media carbon source. After many hours spent running simulations we identified several potential candidates which we are currently working with.

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