Team:ETH Zurich/Modeling/Switch Circuit

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Contents

Switch Circuit

Detailed Model

diffusion of IPTG

diffusion of tet

binding of tetR to LacI-promotor and LacIIs-promotor

binding of LacI and LacIIs to GFP-promotor

binding of tet to tetR

binding of IPTG to LacI

transcription and translation of LacI

transcription and translation of LacIIs

transcription and translation of tetR

transcription and translation of GFP

dimerization of tetR

dimerization and tetramerization of LacI and LacIIs

Implementation

Simulation

Results and Discussion

Parameters

References