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Let us consider the probability of CAI-1 interacting with our fusion kinase with a reaction rate k, diffusion rates D1 and D2 and they start at a distance d apart at the beginning of the time interval<img src="http://lh4.ggpht.com/coa07mhk/SQZQsubfzCI/AAAAAAAAANw/92s3DnMCXMo/s144/delta_t.PNG" />The reaction between two diffusing particles can be considered to take place in two steps. First the encounter of CAI-1 with Fusion kinase and second the actual reaction of passing protein to response regulatory receptor. If we let CAI-1 as entity A and fusion kinase as entity B then the rate of reaction can given as: | Let us consider the probability of CAI-1 interacting with our fusion kinase with a reaction rate k, diffusion rates D1 and D2 and they start at a distance d apart at the beginning of the time interval<img src="http://lh4.ggpht.com/coa07mhk/SQZQsubfzCI/AAAAAAAAANw/92s3DnMCXMo/s144/delta_t.PNG" />The reaction between two diffusing particles can be considered to take place in two steps. First the encounter of CAI-1 with Fusion kinase and second the actual reaction of passing protein to response regulatory receptor. If we let CAI-1 as entity A and fusion kinase as entity B then the rate of reaction can given as: | ||
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<img src="http://lh3.ggpht.com/coa07mhk/SQeGUJunwsI/AAAAAAAAAPo/Viyi5w7QBfA/s400/Pathway.PNG" /> | <img src="http://lh3.ggpht.com/coa07mhk/SQeGUJunwsI/AAAAAAAAAPo/Viyi5w7QBfA/s400/Pathway.PNG" /> | ||
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<img src="http://lh5.ggpht.com/coa07mhk/SQZQ0R3tEeI/AAAAAAAAAPA/N_x0O2WupfY/s800/G1.PNG" /> | <img src="http://lh5.ggpht.com/coa07mhk/SQZQ0R3tEeI/AAAAAAAAAPA/N_x0O2WupfY/s800/G1.PNG" /> |
Revision as of 21:50, 28 October 2008
Let us consider the probability of CAI-1 interacting with our fusion kinase with a reaction rate k, diffusion rates D1 and D2 and they start at a distance d apart at the beginning of the time intervalThe reaction between two diffusing particles can be considered to take place in two steps. First the encounter of CAI-1 with Fusion kinase and second the actual reaction of passing protein to response regulatory receptor. If we let CAI-1 as entity A and fusion kinase as entity B then the rate of reaction can given as: is the probability of interaction between CAI-1 and Fusion Kinase. is the reaction once CAI-1 has interacted with Fusion Kinase. This interaction will follow the law of diffuion and if we let the process under consideration as Poisson process, the probability can be given as: To find the probability of rest of reaction i.e. from activation of UvrY till the shining of our protein we can use the Gaussian Distribution, which can be given as: |
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