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Team:TU Munchen/Projects
From 2008.igem.org
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Contents |
Product Transport in E. Coli (E. Coli Filter)
- Goal: Make E. coli absorb some product.
- Questions:
- What products do we want E. coli to absorb?
- How should E. coli absorb the products?
- Notes:
- Someone should research bioremediation to determine what products cause environmental problems.
- We should understand transport across the cell envelope of Gram-negative bacteria.
- E. coli do transport iron across their cell envelope. A great review is Close Before Opening.
- A starting point for other metals is Structural Analysis and Classification of Native Proteins from E. Coli Commonly Co-Purified by Immobilised Metal Affinity Chromatography.
- Bacteria used for extraction of gold "freeing": Called BIOX Process
Chemotaxis Control (E. Coli Filter and E. Coli Rugby)
- Goal: Make E. coli follow/flee some chemical attractant/repellent.
- Questions:
- How does the chemotactic system work?
- Notes:
Mechanical Stress Detector
- Goal: Make E. coli respond to mechanical stress.
- Questions:
- How does mechanotransduction work in E. coli?
- Notes:
- Sound waves are mechanical stress, so this is an acoustic sensor. We would have to consider some frequency range.
- Read Mechanotransduction: All Signals Point to Cytoskeleton, Matrix, and Integrins and Structure and Function of the Bacterial Mechanosensitive Channel of Large Conductance.
Lipopolysaccharide Detector
- Goal: Make E. coli detect lipopolysaccharide (LPS).
- Notes:
- LPS leads to inflammation in higher organisms.
Light Sensor (E. Coli Sunscreen)
- Goal: Make E. coli respond to varying intensities of light.
