Team:BCCS-Bristol/Modeling

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BCCS-Modelling-Header 01.jpg BCCS-Modelling-Header 02.jpg BCCS-Modelling-Header 03.jpg

Contents

Approach

Modelling Notebook

  • Progress Report - To track our progress see our weekly reports which let you know what we have been up to with comments on the reasons behind any important decisions.
  • Modelling Parameters - Full listings of all parameters investigated for the modelling part of the project, with values that have been chosen, reasons for their selection and references to the original sources.

Models


BCCS-Modelling-GRN Sec.jpg
BCCS-Modelling-Agent Sec.jpg
BCCS-Modelling-Hybrid Sec.jpg
Gene Regulatory Networks (GRNs)
Stochastic Agent Based Simulation
Hybrid Model
To understand the dynamics of genetic networks that we design differental equations are used to model the changes in concentrations of mRNA and proteins. With the project requiring global behaviour to emerge via the physical en masse movement of bacteria, stochastic agent based simulations are used to investigate the viability and limits of different approaches. With the aim of improving simulation accuracy this model integrates the intercellular GRN dynamics with the extra-cellular interactions of the stochastic agent based simulation.

Results

Modelling Photo Album