Team:Freiburg/Project

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Revision as of 21:30, 29 September 2008

Project Report

Parts

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-<P><b>Overall Project:</b></P>
+{{Freiburg2008_Main}}
-This year´s main project is the attempt to create an "artificial receptor-system", featuring extra- and intracellular modules as well as suitable transmembrane regions.<br>
-The intracellular domaine of our receptor is build by halfes of split reporter-proteins that can be reassembled to produce readable output. Each one of these molecule-halfes
-is connected to it´s extracellular domaine by a single-span transmembrane-helix. The extracellular or detecting domaine consists of a protein or peptide with the ability to bind the presented stimulus.<br>
-Now, if a system with two matching receptors is presented the stimulus in a strict, pairwise spacial arrangement, the receptor-molecules are brought together, <br>
-the split reporter-protein reassembles inside the cell and the output can be detected. <br>
-We employ so-called "Origami-DNA" to create the exactly defined stimulus-patterns that are needed to activate our receptors.<br>
-{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
-!align="center"|[[Team:Freiburg|Home]]
-!align="center"|[[Team:Freiburg/Team|The Team]]
-!align="center"|[[Team:Freiburg/Project|The Project]]
-!align="center"|[[Team:Freiburg/Parts|Parts Submitted to the Registry]]
-!align="center"|[[Team:Freiburg/Modeling|Modeling]]
-!align="center"|[[Team:Freiburg/Notebook|Notebook]]
-|}