Team:Paris/Analysis

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Then, we have simulated the FIFO with a negative feedback, in order to observe oscillations. We have obtained the following results :
Then, we have simulated the FIFO with a negative feedback, in order to observe oscillations. We have obtained the following results :
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[[Image:Core_system.jpg|520px|left]][[Image:steady_state.jpg|400px|right]]
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[[Image:Core_system.jpg|520px|left]][[Image:steady_state.jpg|390px|right]]
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Revision as of 08:53, 28 October 2008


Core system


Contents

Purpose of this Section

Now that we have obtained a genetic network corresponding to our project, we will analyse it through modeling. Therefore, you will find in this page the principal results coming from the models, as well as some resulting simulations.

FIFO behaviour

We have designed a model corresponding to the genetic network and we have obtained the following results :

Subsystem1.jpg
Essai with fliAbis.jpg


The parameters found in the papers we have used directly lead to FIFO behaviour !

Oscillations

Then, we have simulated the FIFO with a negative feedback, in order to observe oscillations. We have obtained the following results :

Core system.jpg
Steady state.jpg





The first conclusion one can draw is that, with parameters found in the litterature ('biological parameters') the system reaches a steady state and is far from oscillating. Therefore, we have used the model to infer the modifications (that means the experiments to carry out) that had to be undertaken on the biological system to change its stability.

System Improvements

Basically, we had to explore other possibilities to obtain oscillations.

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Model construction || Model and simulations