"
Team:Paris/Analysis/Design1
From 2008.igem.org
(Difference between revisions)
(→Already existing genetic oscillators and their limits) |
(→Already existing genetic oscillators and their limits) |
||
| Line 5: | Line 5: | ||
Designing a simple genetic network that presents an oscillatory behavior is one of the first challenge synthetic biology overcame. More or less successfully. We can count more than ten synthetic genetic oscillators that have varied period and mechanisms. [http://www.ncbi.nlm.nih.gov/pubmed/16604190?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Raúl GUANTES and Juan F. POYATOS (2006)] studied the most simple oscillators composed of two elements while [http://www.ncbi.nlm.nih.gov/pubmed/10659856?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Michael B. ELOWITZ and Stanislas LEIBLER (2000)] designed the more complex "''repressilator''" (''Table 1''), to quote only the best known. | Designing a simple genetic network that presents an oscillatory behavior is one of the first challenge synthetic biology overcame. More or less successfully. We can count more than ten synthetic genetic oscillators that have varied period and mechanisms. [http://www.ncbi.nlm.nih.gov/pubmed/16604190?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Raúl GUANTES and Juan F. POYATOS (2006)] studied the most simple oscillators composed of two elements while [http://www.ncbi.nlm.nih.gov/pubmed/10659856?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Michael B. ELOWITZ and Stanislas LEIBLER (2000)] designed the more complex "''repressilator''" (''Table 1''), to quote only the best known. | ||
| - | [[Image:Oscillators.jpg| | + | [[Image:Oscillators.jpg|thumb|760px|center|Two examples of genetic oscillators. A : a simple oscillator composed of two elements. B : the repressilator. (Legend : Green arrow : Activation. Red blunt arrow : Inhibition)]] |
== Design of our genetic oscillator : The Feed Forward Loop == | == Design of our genetic oscillator : The Feed Forward Loop == | ||
== Limits of our network == | == Limits of our network == | ||
Revision as of 16:09, 26 October 2008
|
Network Design - Part 1
Creating an oscillatory systemAlready existing genetic oscillators and their limitsDesigning a simple genetic network that presents an oscillatory behavior is one of the first challenge synthetic biology overcame. More or less successfully. We can count more than ten synthetic genetic oscillators that have varied period and mechanisms. Raúl GUANTES and Juan F. POYATOS (2006) studied the most simple oscillators composed of two elements while Michael B. ELOWITZ and Stanislas LEIBLER (2000) designed the more complex "repressilator" (Table 1), to quote only the best known.  Design of our genetic oscillator : The Feed Forward LoopLimits of our network |
