Team:Paris/First page

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{{Paris/Menu}}
{{Paris/Menu}}
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<center><html><div style="color:#275D96; font-size:2em;">Network Analysis</div></html></center>
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<center><html><div style="color:#275D96; font-size:2em;">Grosse GROSSE GROOOOOSSSEEEEE Pomme de Terre !</div></html></center>
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* intro
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= The BacteriO'Clock =
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réactivité
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originalité dans la démarche, poursuivre dans la manière de réaliser la bio sachant qu'on est au début du truc continuer d'innover
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*Enable the systematic engineering of biology
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Have you ever dreamt of a new way of thinking everyday life objects ? Be sure, this will come true, under the form of our BacteriO'Clock ! A simple test tube which contains our modified bacteria will give you the time, directly from living organisms. The hours of the day are color-coded and oscillations ensure the repeated periodic behaviour.
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<embed  width="213" height="160"  src="http://biosynthetique.free.fr/videos/flv_player/flvplayer.swf?autostart=true&amp;repeat&amp;file=http://perso.strepsiade.org/~gvieira/out2.flv" quality="high" type="application/x-shockwave-flash"  allowfullscreen="true" align="right"/>
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*Promote the open and transparent development of tools for engineering biology
 
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bordel nouvelles modélisations multiapproche + conception de protocoles systématiques
 
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rajouter originalité
 
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*Construct a society that can productively apply biological technology
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projet bioplastiques//productivité+ pour l'industrie
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To achieve this incredible project, we relied on a well characterized genetic structure that allows a specific sequence of fluorescent proteins expression to occur in a First In - First Out order. This FIFO behaviour enables us to define a rich color encoding of day time. An additional negative feedback loop generates clock oscillations!
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Based on in-depth studies and experimentally measured parameters we develope models that show that this system is not likely to oscillate, and indicate ways to improve the initial design. In particular, this can be achieved by HSL production that enforces a necessary delay and provides an elegant cell synchronization mechanism :
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[[Image:Unimo.png|center|Simple visualization of our color coded BacteriO'Clock]]
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présentation des résultats  résultat bio ajd volonté d'établir des protocoles, standardiser les processus ingénieriser/montrer que la bio n'est pas trop compliquée a ingénieriser
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In a nutshell, the new trendy item which will make every biologist in your lab jealous will soon be available. Despise a long-cloning period all biobricks and other constructions are now available. Furthermore, we initiated an extensive characterization plan of these parts. If you manage to wait for the updates, you might even get the version which automatically react to daylight saving time ;)
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"Can simple biological systems be built from standard, interchangeable parts and operated in living cells? Or is biology just too complicated to be engineered in this way?"
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*présentation de l'équipe
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multidisciplinaire donc différentes cultures enrichissantes! undergrad 20 personnes en alternances dou organisation
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* liens vers notebook, frezer, oligos...
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*sponsors
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Latest revision as of 01:20, 30 October 2008


Grosse GROSSE GROOOOOSSSEEEEE Pomme de Terre !


The BacteriO'Clock

Have you ever dreamt of a new way of thinking everyday life objects ? Be sure, this will come true, under the form of our BacteriO'Clock ! A simple test tube which contains our modified bacteria will give you the time, directly from living organisms. The hours of the day are color-coded and oscillations ensure the repeated periodic behaviour.

To achieve this incredible project, we relied on a well characterized genetic structure that allows a specific sequence of fluorescent proteins expression to occur in a First In - First Out order. This FIFO behaviour enables us to define a rich color encoding of day time. An additional negative feedback loop generates clock oscillations!

Based on in-depth studies and experimentally measured parameters we develope models that show that this system is not likely to oscillate, and indicate ways to improve the initial design. In particular, this can be achieved by HSL production that enforces a necessary delay and provides an elegant cell synchronization mechanism :

Simple visualization of our color coded BacteriO'Clock

In a nutshell, the new trendy item which will make every biologist in your lab jealous will soon be available. Despise a long-cloning period all biobricks and other constructions are now available. Furthermore, we initiated an extensive characterization plan of these parts. If you manage to wait for the updates, you might even get the version which automatically react to daylight saving time ;)