All the parameters we might have to introduce in our models
expression of the fl-genes observed in [1]
flhDC + fliA → pfliA → fliA → ∅
- is the contribution of flhDC and fliA on pfliA a SUM gate
(see fliL) ?
- It seems that the FlhDC complex is an hexamere, as FlhD4-FlhC2.
flhDC + fliA → pfliL → Z1 → ∅
the contributions of flhDC and fliA in the activity of pfliL appear to be a SUM
[2] :
act_pfliL(flhDC,fliA) = act_pfliL(flhDC,0)+act_pfliL(0,fliA)
is it the same for the other promoters under the influence of both flhDC and fliA ?
flhDC + fliA → pflgA → Z2 → ∅
is the contribution of flhDC and fliA on pflgA a SUM gate
(see fliL) ?
flhDC + fliA → pflgB → Z2 → ∅
is the contribution of flhDC and fliA on pflgB a SUM gate
(see fliL) ?
flhDC + fliA → pflhB → Z3 → ∅
is the contribution of flhDC and fliA on pflhB a SUM gate
(see fliL) ?
lasI → 3OC12HSL → ∅
d[HSL]/dt = -D * Grad²([HSL])
lasR → Rec → ∅
3OC12HSL + Rec → HSL-Rec → ∅
HSL-Rec + pRep → TetR → ∅
∅ → aTc → ∅
TetR + aTc → pTet → flhDC → ∅
OmpR* → pflhDC → flhDC → ∅
References
[1] Ordering Genes in a Flagella Pathway by Analysis of Expression Kinetics from Living Bacteria
S. Kalir, J. McClure, K. Pabbaraju, C. Southward, M. Ronen, S. Leibler, M. G. Surette, U. Alon,
[2] Using a Quantitative Blueprint to Reprogram the Dynamics of the Flagella Gene Network'
'
Shiraz Kalir and Uri Alon
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