Team:Paris/Modeling/Roadmap

From 2008.igem.org

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** see mgs (gillespie or spatialization)
** see mgs (gillespie or spatialization)
** highly rigorous model with mRNA and ON/OFF
** highly rigorous model with mRNA and ON/OFF
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==Bonus ideas==
 
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* optimization of the links in a bio process
 
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* new way to see modeling (stochastic / ON&OFF + mRNA...)
 
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* new way to model noise
 
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* using the noise?
 
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Revision as of 17:50, 8 August 2008

Contents

Calendar

July

  • 07/31 - Have a full bibliography ⇒ DONE

August

  • 06/07 - First model of the FIFO temporal order, of the backward control inducing the oscillations ⇒ DONE
  • 08/07 - Model the synchronization between cells, using Biocham
  • 08/15 - Summary about the ODE method, Space introduction into models (AC, Delaunay)
  • 08/22 - Feedback: list missing things (parameters), Optimization, Robustness analysis

September

  • 09/22- Checkpoint meeting

October

  • 10/15 - Scheduled wiki ending (2 weeks before the real ending to finish details)
  • 10/31 - Official wiki ending (date to be checked)

Todo

  • On the previous model
    • add cells
    • have a population that changes over time
    • Parameters robustness (threshold, Pa) (screening)
    • Gillespie : rebuild the model with this new approach // noise
    • Quantification of FIFO (see Yann)
    • Quantification period (influent parameters...)
  • Other ideas
    • biocham : comparison with adapted repressilator
    • system to add "random" links for model optimisation (quantification of quality : see that oscillation FIFO and synchronization still occur)
    • change place of tetR (on flgA...)
    • see mgs (gillespie or spatialization)
    • highly rigorous model with mRNA and ON/OFF