Team:Paris/Modeling/Molecular Reactions

From 2008.igem.org

(Difference between revisions)

Revision as of 22:28, 29 October 2008

Molecular Reactions

We show here the elementary reactions from wich we started. They intend to be "exhaustives" in the sense that every steps of the system is described. Each of those reactions has to be "mathematically interpreted", in a model which accounts for the important phenomenons, and, in the same time, which allows us to find experimentally every involved parameters.

The system we are studying is the "Core System with three genes of interest" that we can represent in the scheme just below (with all alternatives pFlhDC or pTet and TetR or envZ or OmpR^*)

↓ Core System ↑

core system

The "core systeme"
* Every interactions are modelised by a ƒX function
* The detailed example FP1 = ƒ5([FlhDC],[FliA]) is surrounded in red

Complexation Reactions

The double triangle (><) is a symbol for complexations :
means n₁ molecules of FlhDC complexed with a pFliA promoter

↓ Complexation Reactions ↑

On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

FlhDC and FliA bind to pFliL :

Production Reactions

The double triangle (><) is a symbol for complexations :
means n₁ molecules of FlhDC complexed with a pFliA promoter

↓ Production Reactions ↑

On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

FlhDC><pFliL and FliA><pFliL causes "production" of FP1 :

Degradation/Dilution Reactions

↓ Degradation/Dilution Reactions ↑

On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

FP1 disappears because of its degradation and dilution :

For complete PDF with all Reactions and Numbered References : complete list of reactions and equations

<Back to "Workflow on an Example"|

@@ Line 7: / Line 7: @@
 <br>
-'''The system we are studying is the "'''<span style="color:#0000FF;">Core System</span> '''with three genes of interest"''' that we can represent in the <span style="color:#0000FF;">scheme</span> just below (with all alternatives ''pFlhDC'' or ''pTet'' and ''TetR'' or ''envZ'' or ''OmpR<sup>*</sup>'')
+'''The system we are studying is the "Core System with three genes of interest"''' that we can represent in the scheme just below (with all alternatives ''pFlhDC'' or ''pTet'' and ''TetR'' or ''envZ'' or ''OmpR<sup>*</sup>'')
 <div style="text-align: center">