Team:Wisconsin/Modeling

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Latest revision as of 00:27, 30 October 2008

Computer Modeling

Our modeling adventure started with a brief introduction to programming using GAMS software and an E. coli database developed by Dr. Jennie Reed at the University of Wisconsin College of Engineering. Dr. Reed’s database works in conjunction with the GAMS software to measure metabolic fluxes in E. coli. Using this as a base point we were able to computationally manipulate metabolites, genes, and the growth environment to determine the most optimal conditions for cell growth and hopefully sorbitol production. Glycerol is currently produced at a rate of one pound for every ten pounds of biodiesel produced. Consequently, our team felt it would be interesting if we could find a novel use for glycerol in our pursuit of sorbitol producing E. coli. As such we decided to utilize glycerol as our growth media carbon source. After many hours spent running simulations we identified several potential candidates which we are currently working with.

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+<html><link rel="stylesheet" href="https://mywebspace.wisc.edu/jluo1/wisconsinstyle.css" type="text/css"></html>
-<!--- The Mission, Experiments --->
+<div style="background: #000; padding: 10px;">
-{| style="color:#000;background-color:#C00;" cellpadding="3" cellspacing="1" border="1" bordercolor="#FFF" width="62%" align="center"
+<div style="width:800px; height:147px; border:0px; margin:0px;">[[Image:Igemwibanner.gif]]</div>
+__NOTOC__
+<div class="NavBar">
+{|
 !align="center"|[[Team:Wisconsin|Home]]
 !align="center"|[[Team:Wisconsin/Team|The Team]]
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 !align="center"|[[Team:Wisconsin/Modeling|Modeling]]
 !align="center"|[[Team:Wisconsin/Notebook|Notebook]]
-|}
+|}<br>
+</div>
-(''Or you can choose different headings.  But you must have a team page, a project page, and a notebook page.'')
+<div class="Main">
+==Computer Modeling==
+<br><font color=#aada84>
+Our modeling adventure started with a brief introduction to programming using GAMS software and an ''E. coli'' database developed by Dr. Jennie Reed at the University of Wisconsin College of Engineering.  Dr. Reed’s database works in conjunction with the GAMS software to measure metabolic fluxes in ''E. coli''. Using this as a base point we were able to computationally manipulate metabolites, genes, and the growth environment to determine the most optimal conditions for cell growth and hopefully sorbitol production.  Glycerol is currently produced at a rate of one pound for every ten pounds of biodiesel produced.  Consequently, our team felt it would be interesting if we could find a novel use for glycerol in our pursuit of sorbitol producing ''E. coli''. As such we decided to utilize glycerol as our growth media carbon source.  After many hours spent running simulations we identified several potential candidates which we are currently working with.
-===Note===
+[[Image:Printscreen.JPG|600px]]<br><br>
+[[Image:Printscreen_2.JPG|600px]]<br><br>
-If you choose to include a '''Modeling''' page, please write about your modeling adventures here.  This is not necessary but it may be a nice list to include.
+[[Image:Printscreen_3.JPG|600px]]<br><br>
+[[Image:Printscreen_4.JPG|600px]]<br><br>