"
Team:Paris
From 2008.igem.org
| Line 4: | Line 4: | ||
<br> | <br> | ||
<br> | <br> | ||
| + | <html> | ||
<body background="https://static.igem.org/mediawiki/2008/f/f6/Specmontre.jpg"> | <body background="https://static.igem.org/mediawiki/2008/f/f6/Specmontre.jpg"> | ||
| + | <html> | ||
Have you ever dreamed of a new way of thinking everyday life objects ? Be sure, this will come true, under the form of our BacteriO'Clock ! A simple test tube which contains our modified bacteria will give you the time, directly from living organisms. The hours of the day are color-coded and oscillations ensure the repeated periodic behaviour. | Have you ever dreamed of a new way of thinking everyday life objects ? Be sure, this will come true, under the form of our BacteriO'Clock ! A simple test tube which contains our modified bacteria will give you the time, directly from living organisms. The hours of the day are color-coded and oscillations ensure the repeated periodic behaviour. | ||
<center> | <center> | ||
Revision as of 01:36, 30 October 2008
|
The BacteriO'Clock
To achieve this incredible project, we relied on a well characterized genetic structure that allows a specific sequence of fluorescent proteins expression to occur in a First In - First Out order. This FIFO behaviour enables us to define a rich color encoding of day time. An additional negative feedback loop generates clock oscillations! Based on in-depth studies and experimentally measured parameters we develope models that show that this system is not likely to oscillate, and indicate ways to improve the initial design. In particular, this can be achieved by HSL production that enforces a necessary delay and provides an elegant cell synchronization mechanism : 
We are extremely grateful to the organizations that support our project
|
