Team:NTU-Singapore/Team/Introduction
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- | =[[Team:NTU-Singapore/Project|Project introduction]]= | + | =[[Team:NTU-Singapore/Project|Project introduction: '''G.O.T Colincin?''']]= |
Our group has decided to engineer E.coli as a carrier for ''colicin E7'' to deal with the pathogenic strain of Ecoli known as ''Escherichia coli O157:H7''. | Our group has decided to engineer E.coli as a carrier for ''colicin E7'' to deal with the pathogenic strain of Ecoli known as ''Escherichia coli O157:H7''. | ||
Escherichia coli O157:H7 is an ''enterohemorrhagic strain'' that can cause bloody diarrhea and kidney failure. Current methods of cure for the infection include blood transfusion and dialysis. Currently no antibiotic is able to kill it. | Escherichia coli O157:H7 is an ''enterohemorrhagic strain'' that can cause bloody diarrhea and kidney failure. Current methods of cure for the infection include blood transfusion and dialysis. Currently no antibiotic is able to kill it. | ||
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- | For any comments or enquiries, contact us at [mailto:ntu.igem@gmail.com ntu.igem@gmail.com] | + | For any comments or enquiries, feel free to contact us at [mailto:ntu.igem@gmail.com ntu.igem@gmail.com] |
=Upcoming important events= | =Upcoming important events= |
Revision as of 06:03, 25 October 2008
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Contents |
Team background
This project was done by the NTU@iGEM team consisting of six undergraduate students during the period of May to July 2008. In addition, this project was also assisted by a number of graduate students and faculty advisors whom have given us valued advices and help throughout the project. We would like to extend our gratitude to everyone who has helped us during the course of our project, please kindly refer to the Acknowledgements for more details.
Students
Faculty Advisors
Student HelperLu Chao (Year 4 Bio-Engineering Student)
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Project introduction: G.O.T Colincin?
Our group has decided to engineer E.coli as a carrier for colicin E7 to deal with the pathogenic strain of Ecoli known as Escherichia coli O157:H7. Escherichia coli O157:H7 is an enterohemorrhagic strain that can cause bloody diarrhea and kidney failure. Current methods of cure for the infection include blood transfusion and dialysis. Currently no antibiotic is able to kill it.
Our approach is to use Colicin E7 to kill this harmful strain of bacteria. We intend to use our very own genetically engineered E.coli as the carrier of the colicin. We also wish for our bacteria to able to detect the presence of blood and the bacteria before it releases the colicins to eradicate the pathogen.
Our aim would be to control the level of colicin production in our bacteria. Our engineered bacteria should also be able to be accurate in its detection.
For any comments or enquiries, feel free to contact us at ntu.igem@gmail.com
Upcoming important events
1 July | Team project descriptions due (Early summer teams) |
Team registration fee due | |
1 September | Final team rosters due |
1 October | Jamboree attendance fees due; notice and description of any use of non-standard parts or devices schemes due |
15 October | Project Summary forms due (to allow for organization of judging) |
29 October | Project and part documentation due |
29 October | BioBrick Part DNA received by the Registry |
8-9 November | iGEM Competition Jamboree, MIT, USA |