Team:Paris/Network analysis and design/System improvements

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Revision as of 01:27, 26 October 2008

System Improvements

Synchronized oscillations should be given by S2.
Name	Description	Evaluation	Links
Core system	Figure core system	File:Equilibrium.jpg	Links core system
Modular system	Figure modular system	File:Damped.jpg	Links Garcia-Ojalvo
Resulting system	Figure resulting system	File:Oscillating.jpg	Links resulting

Core system does not oscillate. How can we enhance it?

We need a 'delay' so we can:

1 add more genes to the circuit

2 use quorum sensing (qs)

we chose quorum sensing that can allowed both 'delay' and population synchonization. two ways to add it:

S4: Inspired from Garcia-Ojalvo: oscillating repressilator + oscillating qs module = synchronized oscillations

S2: it amounts to replace single interaction by more complex interactions: should create delay

we analyze both systems for their capacity to generate oscillations. S2 seems more promising. Thus we further analize S2 for its capacity to generate synchrionized oscillations.

@@ Line 11: / Line 11: @@
 | style="background: #D4E2EF;"|Core system
 | Figure core system
-| [[Image:Orgsad.gif‎]]
+| [[Image:Equilibrium.jpg]]
 | Links core system
 |- style="background: #dddddd;"
 | style="background: #D4E2EF;" |Modular system
 | Figure modular system
-| [[Image:Orgstar.gif]][[Image:Orgstar.gif]]
+| [[Image:Damped.jpg]]
 | Links Garcia-Ojalvo
 |- style="background: #dddddd;"
 | style="background: #D4E2EF;" |Resulting system
 | Figure resulting system
-| [[Image:Orgstar.gif]][[Image:Orgstar.gif]][[Image:Orgstar.gif]]
+| [[Image:Oscillating.jpg]]
 | Links resulting
 |- style="background: #dddddd;"