Team:Brown

From 2008.igem.org

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     <td>Around the world, contamination of drinking water is an immense  problem that is difficult and expensive to detect with current  technology. As such, many Third World countries are unable to  effectively diagnose the problem across the millions of water supply  sources that exist.  There is a need for an economically feasible, transportable, and  user-friendly detection system for water contamination that can  reliably be used in the field. </p>
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     <td><p>Brown iGEM's 2008 Team focused on designing a novel electrical reporting system that has applications in toxin detection, particularly for third-world countries, where water pollution is prevalent. </p>
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    <p>Our work focuses on designing and implementing a novel  biosensor that reports information back in a simple electric signal. Our biosensor will have the ability to detect the presence of certain inducers (for example a water contaminant or toxin), and report that information back via a change in the conductance of the bacterial solution. An inducer specific promoter transcribes and leads to the subsequent translation of a “Lysis Gene Cassette.” Lysis of the  bacteria results in the release of the bulk intracellular ionic content  into the surrounding media, causing the solution’s conductivity to increase, thereby indicating the presence of the inducer. </p></td>
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      <p>Our biosensor has the ability to detect the presence of a certain inducer (for example a water contaminant or toxin), and report that information back via a change in the conductance of the bacterial solution using a Lysis Gene Cassette bound to an inducible promoter.</p>
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    <td><div style="width:425px;text-align:left" id="__ss_695236">
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      <p>See the video for a team &amp; project overview!</p>
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       <object style="margin:0px" width="425" height="355"><param name="movie" value="http://static.slideshare.net/swf/ssplayer2.swf?doc=resistance-4-updates-1225059052545214-8&rel=0&stripped_title=brown-igem-toxipop-presentation-presentation" /><param name="allowFullScreen" value="true"/><param name="allowScriptAccess" value="always"/><embed src="http://static.slideshare.net/swf/ssplayer2.swf?doc=resistance-4-updates-1225059052545214-8&rel=0&stripped_title=brown-igem-toxipop-presentation-presentation" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="425" height="355"></embed></object>
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       <p><img src="https://static.igem.org/mediawiki/2008/d/d5/Brown_igem.png" width="337" height="267" border="0" align="center"/></p>
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      <div style="font-size:11px;font-family:tahoma,arial;height:26px;padding-top:2px;">View SlideShare <a style="text-decoration:underline;" href="http://www.slideshare.net/neilparikh/brown-igem-toxipop-presentation-presentation?type=powerpoint" title="View Brown iGEM Toxipop Presentation on SlideShare">presentation</a>.</div>
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      <p>&nbsp;</p>
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    <p>&nbsp;</p>
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    <td><embed src="http://blip.tv/play/AdX1EpDPGQ" type="application/x-shockwave-flash" width="510" height="408" allowscriptaccess="always" allowfullscreen="true"></embed> </td>
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Revision as of 07:32, 27 October 2008



Brownwelcome.png

Brown iGEM's 2008 Team focused on designing a novel electrical reporting system that has applications in toxin detection, particularly for third-world countries, where water pollution is prevalent.

Our biosensor has the ability to detect the presence of a certain inducer (for example a water contaminant or toxin), and report that information back via a change in the conductance of the bacterial solution using a Lysis Gene Cassette bound to an inducible promoter.

See the video for a team & project overview!

 

 

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