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Team:Paris/Modeling/Workflow Example
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As it is illustrated below; starting from ''molecular reactions'' '''(1)''', we develop a ''model of our system'' '''(2)''', and then we identify the ''parameters'' '''(3)''' that needs to be estimated. Essentially, it amounts to estimate ''Promoters Activities as functions of their Transcription Factors''. To do so, we propose ''constructs'' '''(4)''', ''protocols'' '''(5)''' and ''programs'' '''(6)'''. | As it is illustrated below; starting from ''molecular reactions'' '''(1)''', we develop a ''model of our system'' '''(2)''', and then we identify the ''parameters'' '''(3)''' that needs to be estimated. Essentially, it amounts to estimate ''Promoters Activities as functions of their Transcription Factors''. To do so, we propose ''constructs'' '''(4)''', ''protocols'' '''(5)''' and ''programs'' '''(6)'''. | ||
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| - | <center><span style="color: red; font-weight: bold; font-size: 16"> | + | <center><span style="color: red; font-weight: bold; font-size: 16">CLICK on the images below for further informations on each step!</span></center> |
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Revision as of 23:41, 29 October 2008
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Characterization Approach : Generic Workflow on an Example
Here, we will explain the generic protocol that leads to the modelisation "by characterization", of one of the parts of our system. The choosen example is the activity of the promoter pFliL (that leads to the production of the Fluorescent Protein FP1) in function of the transcription factors FlhDC and FliA .
We know that the hexamere FlhD4C2 and the protein FliA act both on the promoter pFliL as inducers... how do we evaluate this phenomenon?
Once we got every parameters for every functions involved in our Full System, we have got a "Modular Virtual Lab" of our System that aims to be predictive.
↓ Details on the Steps ↑
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