Team:Paris/Modeling/Molecular Reactions

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[[https://2008.igem.org/Team:Paris/Modeling/Workflow_Example| Back to the "Workflow on an Example"]]
We show here the elementary reactions from wich we started. They intend to be "exhaustives" in the sense that every steps of the <span style="color:#0000FF;">system</span> is described. Each of those reactions has to be "mathematically interpreted", in a <span style="color:#0000FF;">model</span> which accounts for the important phenomenons, and, in the same time, which allows us to find <span style="color:#0000FF;">experimentally</span> every involved parameters.
We show here the elementary reactions from wich we started. They intend to be "exhaustives" in the sense that every steps of the <span style="color:#0000FF;">system</span> is described. Each of those reactions has to be "mathematically interpreted", in a <span style="color:#0000FF;">model</span> which accounts for the important phenomenons, and, in the same time, which allows us to find <span style="color:#0000FF;">experimentally</span> every involved parameters.

Revision as of 04:09, 27 October 2008

Molecular Reactions


[Back to the "Workflow on an Example"]

We show here the elementary reactions from wich we started. They intend to be "exhaustives" in the sense that every steps of the system is described. Each of those reactions has to be "mathematically interpreted", in a model which accounts for the important phenomenons, and, in the same time, which allows us to find experimentally every involved parameters.


The system we are studying is the "Core System with three genes of interest" that we can represent in the scheme in the precisions just below (with all alternatives pFlhDC or pTet and TetR or envZ or OmpR*)

↓ precisions ↑


core system

The "core systeme"
* Every interactions are modelised by a ƒX function
* The detailed example FP1 = ƒ5([FlhDC],[FliA]) is surrounded in red


Complexation Reactions

The double triangle (><) is a symbol for complexations :
Compl.jpg means n1 molecules of FlhDC complexed with a pFliA promoter

 On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

  • FlhDC and FliA bind to pFliL :

DCiLcompl.jpg

AiLcompl.jpg

Production Reactions

The double triangle (><) is a symbol for complexations :
Compl.jpg means n1 molecules of FlhDC complexed with a pFliA promoter

 On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

  • FlhDC><pFliL and FliA><pFliL causes "production" of FP1 :



BFP1.jpg

Degradation/Dilution Reactions

On the Example :

How given amounts of FlhDC and FliA would produce FP1 ?

  • FP1 disappears because of its degradation and dilution :

DFP1.jpg


for complete .pdf with all reactions and references : [list of reactions/equations]
Retrieved from "http://2008.igem.org/Team:Paris/Modeling/Molecular_Reactions"