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m sensing</strong>-----Th | m sensing</strong>-----Th | ||
- | at is the way how various bacteria “talk” to each other. It is the mechanism ensures that certain genes will keep silent before the cell density of the species pass a threshold. </span><img src="../ | + | at is the way how various bacteria “talk” to each other. It is the mechanism ensures that certain genes will keep silent before the cell density of the species pass a threshold. </span><img src="https://static.igem.org/mediawiki/2008/b/b3/F2620Parts.png" width="223" height="48"></p></td> |
<td width="329" bordercolor="#03438A" bgcolor="#03438A"><p class="STYLE5"><span class="STYLE9"><strong>Prisoners’ Dilemma----</strong>It is the dilemma in which the two suspects could either choose to cooperate with or betray each other. In conditions when they could communicate freely with each other, they will cooperate, which maximizes their benefits as a whole; while when they are inquisited separately, they will both choose to betray one another to lower the risks of long sentence. </span></p></td> | <td width="329" bordercolor="#03438A" bgcolor="#03438A"><p class="STYLE5"><span class="STYLE9"><strong>Prisoners’ Dilemma----</strong>It is the dilemma in which the two suspects could either choose to cooperate with or betray each other. In conditions when they could communicate freely with each other, they will cooperate, which maximizes their benefits as a whole; while when they are inquisited separately, they will both choose to betray one another to lower the risks of long sentence. </span></p></td> | ||
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<p>When auto-inducers, either AHL or BHL is introduced to the culture, LuxPr or Prhl will be activated to produce the auto-inducers required by their partners, and express the anti-biotic resistant genes to ensure each other’s survival. During the process, PBad/arac and Plac will be repressed because of the repressors Arac and LacI expressed by LuxPr and PrhI. </p> | <p>When auto-inducers, either AHL or BHL is introduced to the culture, LuxPr or Prhl will be activated to produce the auto-inducers required by their partners, and express the anti-biotic resistant genes to ensure each other’s survival. During the process, PBad/arac and Plac will be repressed because of the repressors Arac and LacI expressed by LuxPr and PrhI. </p> | ||
<p>However, upon the introduction of IPTG or arobinose, the repressors will stop functioning, so that Aiia will be expressed, and therefore AHL and BHL will be degraded, so that there will be no communications any more, and the relationship between the two strains will enter the phase of competition. </p></td> | <p>However, upon the introduction of IPTG or arobinose, the repressors will stop functioning, so that Aiia will be expressed, and therefore AHL and BHL will be degraded, so that there will be no communications any more, and the relationship between the two strains will enter the phase of competition. </p></td> | ||
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</table> <p><span class="STYLE9" style="margin-bottom: 0">This idea was inspired by the theory of Prisoner’s Dilemma. | </table> <p><span class="STYLE9" style="margin-bottom: 0">This idea was inspired by the theory of Prisoner’s Dilemma. | ||
- | + | As in prisoners’ dilemma, the bacteria in our design are faced with two solutions for coexistence, they could either choose to cooperate with one another by providing inducers to express their partners’ antibiotics-resistance genes or they could take a foe strategy in which no cooperation is needed for both strains’ survival.</span></p> | |
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Revision as of 07:37, 28 October 2008
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This idea was inspired by the theory of Prisoner’s Dilemma. As in prisoners’ dilemma, the bacteria in our design are faced with two solutions for coexistence, they could either choose to cooperate with one another by providing inducers to express their partners’ antibiotics-resistance genes or they could take a foe strategy in which no cooperation is needed for both strains’ survival. |
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