Team:Paris/Modeling

Roadmap

If you want to have a look at our roadmap : Roadmap

Bibliography

In order to choose a proper modeling approach for our system, we have decided to list all the chemical reactions we will take into account. Afterwards, we will find the needed parameters reading articles or devising the required experiments.

An overview of the work that has to be done can be found here : Bibliography

Estimation of parameters

If we want to use the promoters used for the formation of the flagella ( Description of the project), we will have to clearly defined their dynamics. To do so, a rather huge experimental work will be undertaken, consisting in providing the so-called 'Hill functions' for each promoters.

Therefore, we have written a little module which can estimate the parameters of the 'Hill functions', even with some noise and few data available. Some details and the corresponding code can be found here : Programs.

The method we have employed is just based on a least-square optimization. Then, it could be generic enough for many applications and we would be glad to share the code if you feel it could be usefull.