Team:Rice University

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Welcome to Rice University's 2008 iGEM wiki page. We have two new projects this year!
Our primary project is BIOBEER, where we are genetically engineering the biosynthetic pathway for resveratrol production into a brewing yeast strain. Resveratrol has been shown to have a plethora of health benefits, including anti-cancer and anti-viral activity, cardio- and neuro-protective effects, modulation of diabetes, and anti-aging effects. Although research has been done previously to produce resveratrol in various organisms, no one to date has developed a yeast strain able to synthesize resveratrol in a de novo manner. We are going one step further, characterizing resveratrol production during anaerobic fermentation with the intent of creating a beer that contains all the health benefits of wine. Get ready for resveratrol in a fizzy ready-to-consume beverage!

Our second project looks at the potential of using phage as a signal amplification system. When a bacterial population is infected by bacteriophage, there is an exponential increase in the number of phage particles produced. By designing phage in which the replication of the phage is coupled to some environmental stimulus, such as the presence of another bacterium, we can produce an extremely sensitive biodetector.


(More detailed descriptions of projects to be added.)

BioBeer: Producing Resveratrol During Fermentation in Beer

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Stuff about Beer HERE











Phage Signal Amplifier Project








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