Team:Valencia/Project/Results

Achievements

We have:
1.- Developed a brand new instrument: LCC (Liquid Culture Calorimeter) for real-time, high precision measurement of the internal temperature of a thermically isolated liquid culture. This instrument is a new technical standard that supports the characterization of other temperature-related BioBricks Parts or Devices.
2.- Demonstrated, for the first time, that UCP-1 (termogenin) is, as expected, able to produce a significant increase in temperature in recombinant UCP-expressing yeasts.
3.- Characterized four new biobricks (a UCP-expressing yeast, a control strain and two mutant strains with enhanced uncoupling activity) through temperature measurements with the LCC, as well as from relative growth data of the yeast cultures.
4.- Outlined a new approach to Human Practices in Synthetic Biology by writing a Proposal for a Code, that includes a novel concept: concentric ethical units, that might be very useful not only for the Hot Yeast Project but also for any Synthetic Biology research.