Purdue/11 June 2008
From 2008.igem.org
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Lab Meeting
In attendance:
- Craig Barcus
- Janie Stine
- Michael Iannotti
- David Jaroch
- Dr. Jenna Rickus
- Dr. Bernard Tao
Minutes
- Discussed unfeasibility of Milk spoilage idea
- According to consumer standards, milk pH need only decrease 0.2 pH units (from 6.6 to 6.4) before it is considered unacceptable
- Lactose and lactobacilli pathways are too subtle to be able to detect with bacteria
- Idea not commercially useful
- Brainstormed a lot
- NEW IDEA: UV sensor
- Changes color when under UV light for too long (dangerous levels)
- Use naturally existing DNA repair pathways (RecA)
- Make into a patch form that could be stuck onto skin or clothing
- Patch would have a vital nutrient to keep colonies on patch
- Possible patch = liquid band-aid?
- Components
- Promoter from a DNA-repair pathway natural to E. coli or other bacteria (RecA?) -- See Dave
- Something that colors the bacteria:
- Could be a colored protein or metabolic color
- It's better if it's from an enzyme pathway--easier to control
- Want it to be degradable so that the color fades when you're not in the sun
- Also need a method for a patch
- Needs to be able to sustain bacterial growth without contaminating humans, etc.
- Possible uses:
- Sunscreen
- Clothing
- Hair Dye
- Tatoos
- "Invisible Ink"
Edited by Janie Stine