Team:ETH Zurich/Modeling/Genome-Scale Model

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In the [[Team:ETH_Zurich/Modeling/Genome_Static_Analysis|'''Restriction Enzymes Analysis''']] modeling section we deal with the analysis of restriction enzymes effects on the genome from the simple point of view of nucleotide sequences and cutting patterns.  
In the [[Team:ETH_Zurich/Modeling/Genome_Static_Analysis|'''Restriction Enzymes Analysis''']] modeling section we deal with the analysis of restriction enzymes effects on the genome from the simple point of view of nucleotide sequences and cutting patterns.  
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This is not informative enough when we try to understand if the key principles of reduction and selection at the base of our minimal genome approach are valid in the context of the whole cell response. It is evident that our selection method for smaller genome size strains is based on the assumption that is possible to control growth rate as a function of its genome size. As explained in the [[Team:ETH Zurich/Project/Overview|Project Overview]]  
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This is not informative enough when we try to understand if the key principles of reduction and selection at the base of our minimal genome approach are valid in the context of the whole cell response. It is evident that our selection method for smaller genome size strains is based on the assumption that is possible to control growth rate as a function of its genome size. As explained in the [[Team:ETH Zurich/Project/Overview|Project Overview]], we put a selective pressure on the genome size 
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=== Genome Scale Models ===
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=== Thymidine limitation effects on growth rates ===
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=== Genome size effects on growth rates ===
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=== Different mediums ===
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=== Growth rates as output of whole cell system behaviour ===
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Revision as of 12:31, 26 October 2008


Contents

Genome Scale Analysis

In the Restriction Enzymes Analysis modeling section we deal with the analysis of restriction enzymes effects on the genome from the simple point of view of nucleotide sequences and cutting patterns. This is not informative enough when we try to understand if the key principles of reduction and selection at the base of our minimal genome approach are valid in the context of the whole cell response. It is evident that our selection method for smaller genome size strains is based on the assumption that is possible to control growth rate as a function of its genome size. As explained in the Project Overview, we put a selective pressure on the genome size

Genome Scale Models

Thymidine limitation effects on growth rates

Genome size effects on growth rates

Different mediums

Growth rates as output of whole cell system behaviour

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