Team:Paris/Analysis/Construction2
From 2008.igem.org
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+ | <TD COLSPAN=2 BGCOLOR="#649CD7"><B>Common Network Dynamics: FlhDC and Flia </B></TD> | ||
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- | <TD COLSPAN=2> | + | <TD COLSPAN=2> FlhDC and Flia are regulated in the same way in both systems. FlhDC is produced under the influence of EnvZ via an inhibition. Flia is regulated for its self and FlhDC. </TD> |
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- | <TD COLSPAN=2>[[Image: | + | <TD COLSPAN=2>[[Image:FlhDC-FliaEq.png|550px]] </TD> |
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+ | <TD COLSPAN=2> a) The expression of ''lasI'' is under the control of the same promotor that used for FlhDC.</TD> | ||
+ | <TD COLSPAN=2> a) The expression of ''lasI'' is regulated by FlhDC and Flia (as in the core system). </TD> | ||
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- | <TD COLSPAN=2> | + | <TD COLSPAN=2> b) The expression of ''envZ'' depends on both the activation from FlhDC and Flia (as in the core system) and the concentration of HSL present in the cell.</TD> |
- | <TD COLSPAN=2> | + | <TD COLSPAN=2> b) The expression of ''envZ'' varies as a function of the concentration of HSL present in the cell.</TD> |
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Revision as of 00:11, 28 October 2008
Model Construction
MotivationWe are interested to understand the factors that account for an oscillating behaviour at population level. We build two models to study systems that are equipated with quorum sensing capabilities but that relay on different designs principles. The proposed models are:
Both the bimodular and unimodular models describe events that happend not only at the cellular level (as in the core system) but also at the population level due to interactions needed bettwen a cell and its environment during quorum sensing. In the following sections, we first describe the population modeling (the common part amoung our two proposed models) to then focus our attention to the characteristics that are exclusive to each of the modeling alternatives. Description
Parameters SearchThe following table sumarize our findings. The parameters' values that are used during the simulations. Most them are found in literature others are obtained from further analysis.
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