Team:Paris/Analysis/Construction2
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The proposed models are: | The proposed models are: | ||
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+ | <TABLE> | ||
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+ | <TD COLSPAN=2 BGCOLOR="#D4E2EF"><B>Bimodular System</B></TD> | ||
+ | <TD COLSPAN=2 BGCOLOR="#D4E2EF"><B>Unimodular System</B></TD> | ||
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+ | <TR ALIGN=CENTER VALIGN=MIDDLE> | ||
+ | <TD COLSPAN=2>[[Image:Bimo.png|550px]]Core system coupled with an oscillator</TD> | ||
+ | <TD COLSPAN=2>[[Image:Unimo.png|550px]]Modified core system that accounts for quorum sensing</TD> | ||
+ | </TR> | ||
+ | </TABLE> | ||
+ | </CENTER> | ||
*In the one model, we use a modular design. We consider that the core system is one of the modules of the system. In adittion, the other module is an two gene oscillator system presented in [[Team:Paris/Modeling/BOB#Bibliography|[Garcia-Ojalvo]]] that accounts for quorum sensing. We call this alternative the 'bimodular system'. | *In the one model, we use a modular design. We consider that the core system is one of the modules of the system. In adittion, the other module is an two gene oscillator system presented in [[Team:Paris/Modeling/BOB#Bibliography|[Garcia-Ojalvo]]] that accounts for quorum sensing. We call this alternative the 'bimodular system'. |
Revision as of 13:06, 28 October 2008
Model Construction
IntroductionWe are interested to understand the factors that account for an oscillating behaviour at population level. We build two models to study systems that are equipated with quorum sensing capabilities but that relay on different designs principles.↓ Joint our quest for alternatives... ↑
Modeling AlternativesThe proposed models are:
Both the bimodular and unimodular models describe events that happend not only at the cellular level (as in the core system) but also at the population level due to interactions needed bettwen a cell and its environment during quorum sensing. In the following sections, we first describe the population modeling (the common part amoung our two proposed models) to then focus our attention to the characteristics that are exclusive to each of the modeling alternatives. Description
↓ more detailed description... ↑
Parameters SearchThe following table sumarize our findings. The parameters' values that are used during the simulations. Most them are found in literature others are obtained from further analysis.
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