Team:Paris/Modeling/FromMolReactToNLOde
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(New page: {{Paris/Menu}} {{Paris/Header|From Molecular Reactions to Non-Linear ODEs}} We must here propose a Mathematical Modeling of the <span style="color:#0000FF;">elementary molecular reaction...) |
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{{Paris/Header|From Molecular Reactions to Non-Linear ODEs}} | {{Paris/Header|From Molecular Reactions to Non-Linear ODEs}} | ||
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+ | = Idea and Assumptions = | ||
We must here propose a Mathematical Modeling of the <span style="color:#0000FF;">elementary molecular reactions</span>. The idea of the ''Characterization Approach'' is that this modelization must both accounts for <span style="color:#0000FF;">every small steps</span> of the system and allow the <span style="color:#0000FF;">experimental characterizations</span>. | We must here propose a Mathematical Modeling of the <span style="color:#0000FF;">elementary molecular reactions</span>. The idea of the ''Characterization Approach'' is that this modelization must both accounts for <span style="color:#0000FF;">every small steps</span> of the system and allow the <span style="color:#0000FF;">experimental characterizations</span>. | ||
- | Therefore, the following equations do not describe properly what ''really'' happens in the cells. For exemple, we know that the transcription factor FlhD-FlhC is actually an ''hexamere FlhD<sub>4</sub>C<sub>2</sub>''. But, as we will surely not get access to the ''dissociation constant'' of the ''hexamerisation'', we just treat it as an ''abstract'' inducer protein "FlhDC", with an order (''n'') in its ''complexation | + | <div style="text-align: center"> |
+ | {{Paris/Toggle|precisions|Team:Paris/Modeling/More_From2Ode_Intro}} | ||
+ | </div> | ||
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+ | Therefore, the following equations do not describe properly what ''really'' happens in the cells. For exemple, we know that the transcription factor FlhD-FlhC is actually an ''hexamere FlhD<sub>4</sub>C<sub>2</sub>''. But, as we will surely not get access to the ''dissociation constant'' of the ''hexamerisation'', we just treat it as an ''abstract'' inducer protein "''FlhDC''", with an order (''n'') in its ''complexation caracterization'' probably around 2*4 = 8 (but perhaps completly different ! ; the estimation of the error by the <span style="color:#0000FF;">parameter finder program</span> will tell us if we are consistent). | ||
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+ | <div style="text-align: center"> | ||
+ | {{Paris/Toggle|precisions|Team:Paris/Modeling/More_From2Ode_Expl}} | ||
+ | </div> |
Revision as of 00:56, 27 October 2008
From Molecular Reactions to Non-Linear ODEs
Idea and AssumptionsWe must here propose a Mathematical Modeling of the elementary molecular reactions. The idea of the Characterization Approach is that this modelization must both accounts for every small steps of the system and allow the experimental characterizations. ↓ precisions ↑
Therefore, the following equations do not describe properly what really happens in the cells. For exemple, we know that the transcription factor FlhD-FlhC is actually an hexamere FlhD4C2. But, as we will surely not get access to the dissociation constant of the hexamerisation, we just treat it as an abstract inducer protein "FlhDC", with an order (n) in its complexation caracterization probably around 2*4 = 8 (but perhaps completly different ! ; the estimation of the error by the parameter finder program will tell us if we are consistent). ↓ precisions ↑
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