Team:Paris/Analysis/Math+Sim
From 2008.igem.org
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* Try to change the parameters of the core system (see below). | * Try to change the parameters of the core system (see below). | ||
* Try to device a novel system, based on the previous one (see the section [[Team:Paris/Network_analysis_and_design/System_improvements|System Improvements]]). | * Try to device a novel system, based on the previous one (see the section [[Team:Paris/Network_analysis_and_design/System_improvements|System Improvements]]). | ||
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After testing our [[Team:Paris/Network_analysis_and_design/Core_system/Mathematical_analysis_and_simulations/Analysis_core_system_details|list of the possiblities]], our main findings are: | After testing our [[Team:Paris/Network_analysis_and_design/Core_system/Mathematical_analysis_and_simulations/Analysis_core_system_details|list of the possiblities]], our main findings are: | ||
Revision as of 10:51, 26 October 2008
Mathematical analysis and simulations
FIFO
where CFP, YFP, and RFP will be denoted below as respectively Z1,Z2 and Z3.
We have implemented this system using Matlab (see the corresponding codes)
Indeed, we may see that there is a LIFO behavior rather than the FIFO we expect...
Oscillations
If you want more details about the way we have built them, you can go to the model construction page. If one tries to draw simulations of this system, he will obtain this kind of results : In a nutshell : It does not work !
Finally, the logical continuation of the process will be to try to improve the biological system in order to find oscillations. This will be described in the part below, as well as in the section System Improvements. Parameters' changesSince the core system has difficulties to produce oscillations, we perform a parameter search and we study the impact of parameters' changes in the core system. We brain-storm about possible modifications on the core system. We end up with two main possibilities :
After testing our list of the possiblities, our main findings are: |