Team:KULeuven/Model/Filter
From 2008.igem.org
(Difference between revisions)
m |
m |
||
Line 101: | Line 101: | ||
|[[Image:Sim_filter_long.jpg|450px]] | |[[Image:Sim_filter_long.jpg|450px]] | ||
|} | |} | ||
+ | |||
+ | === Sensitivity Analysis === |
Revision as of 12:58, 7 August 2008
dock/undock dropdown
Contents |
Filter
Position in the system
Describing the system
ODE's
Parameters
Name | Value | Comments | Reference |
---|---|---|---|
Degradation rates | |||
dpT7_tag | 0.00155 s-1 | tag added to speed up degradation of otherwise too stable T7 polymerase | [http://www.openwetware.org/wiki/IGEM:Tsinghua/2007/Projects/RAP#Model_and_simulation link] |
dmRNA_RIBOKEY | 0.00462 s-1 | [http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=124983&blobtype=pdf link] | |
dclosed_mRNA_T7 | 0.00462 s-1 | [http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=124983&blobtype=pdf link] | |
dopen_mRNA_T7 | 0.00231 s-1 | [http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=124983&blobtype=pdf link] | |
dopen_mRNA_T7_complex | 0.00231 s-1 | [http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=124983&blobtype=pdf link] | |
Equilibrium constants | |||
Keq_1 | 0,015 [M] | closed and open mRNA | |
Keq_2 | 0.0212 [M] | closed and key (binded with ribokey) complex mRNA | |
Transcription rates | |||
kmRNA_RIBOKEY | Input dependent | ||
kmRNA_T7 | 0,0011 s-1 |
Models
CellDesigner (SBML file)
Matlab (SBML file)
Matlab diagram for the filter system: