Team:TUDelft/Color modeling

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Revision as of 14:10, 26 August 2008

>> work in progress

Color Modeling

In the output we use mevalonate and GPP pathways together to produce red, orange and yellow colors. The biosynthetic model is built in CellDesigner™. There are 14 subtrates and 13 enzymes in total. The first subtrate is Acetyl-CoA which is provided to the pathway in a constant level. The last three subtrates are the color products and are consuming so we have degradation links for them. Lycopene, B-carotene and Zeaxanthin give red, orange and yellow colors respectively.

Color Pathway

For the 14 reactions of enzyme-subtrate the Michaelis-Menten kinetics is applied and we have the mass action kinetics for the three degradations. According to the kinetic laws there are 14 differential equations for enzyme-subtrate reactions and three for degradations which could be constructed as:

x₁ to x₁₄ are the subtrates.

... to be continued ;)

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 In the output we use [http://www.lbl.gov/Science-Articles/Archive/assets/images/2004/Mar-24/Engineering_terpenoids.pdf mevalonate] and [http://parts.mit.edu/igem07/index.php/Image:Zeaxanthin.jpg GPP] pathways together to produce red, orange and yellow colors.
-The biosynthetic model is bulit in '''CellDesigner&trade;'''. There are 14 subtrates and 13 enzymes in total. The first subtrate is Acetyl-CoA which is provided to the pathway in a constant level. The last three subtrates are the color products and are consuming so we have degradation links for them. Lycopene, B-carotene and Zeaxanthin give red, orange and yellow colors respectively.
+The biosynthetic model is built in '''CellDesigner&trade;'''. There are 14 subtrates and 13 enzymes in total. The first subtrate is Acetyl-CoA which is provided to the pathway in a constant level. The last three subtrates are the color products and are consuming so we have degradation links for them. Lycopene, B-carotene and Zeaxanthin give red, orange and yellow colors respectively.
 [[Image:Mevalonate.jpg |550px|center]]