"
Team:TUDelft/Color modeling
From 2008.igem.org
| Line 26: | Line 26: | ||
We used hill type model for enzyme temperature relations where e<sub>1</sub> to e<sub>13</sub> are the enzymes. | We used hill type model for enzyme temperature relations where e<sub>1</sub> to e<sub>13</sub> are the enzymes. | ||
| - | ... to be continued | + | ... to be continued |
{{Template:TUDelftiGEM2008_sidebar}} | {{Template:TUDelftiGEM2008_sidebar}} | ||
Revision as of 09:50, 3 September 2008
>> work in progress
Color Modeling
In the output we use mevalonate and GPP pathways together to produce red, orange and yellow colors. The biosynthetic model is built in CellDesigner™. There are 14 substrates and 13 enzymes in total. The first substrate is Acetyl-CoA which is provided to the pathway in a constant level. The last three substrates are the color products and are consuming so we have degradation links for them. Lycopene, B-carotene and Zeaxanthin give red, orange and yellow colors respectively.
For the 14 reactions of enzyme-substrate the Michaelis-Menten kinetics is applied and we have the mass action kinetics for the three degradations.
According to the kinetic laws there are 14 differential equations for enzyme-subtrate reactions and three for degradations which could be constructed as:
x1 to x14 are the subtrates.
We used hill type model for enzyme temperature relations where e1 to e13 are the enzymes.
... to be continued
